Over time lifestyle factors can cause reduced elasticity in cartilage, tendons, ligaments and skin. This not only leads to wrinkles and decreased dermal matrix, but to soft tissue and joint discomfort. Collagen-T has been shown in human studies to stimulate collagen regeneration, type II collagen and aggrecan, which all help to maintain healthy connective tissue. Most therapies simply block joint pain and connective tissue discomfort, and in doing so inhibit the regeneration and elongation of specific precursors, such as polysaccharides, and deplete nutrients such as vitamin C and magnesium that maintain joint and connective tissue health. Collagen-T, TendoActive® and Mobilee® protect and preserve cartilage, tendons, ligaments, intervertebral discs, and fascia. These patented ingredients support the natural healing process and maintain the structure of connective tissues.
FORTIGEL®, backed by more than fifteen studies, provides bioactive collagen peptides (BCPs), which contain high concentrations of specific peptides that comprise connective tissue. The precise length of the short-chain peptides and low average molecular weight allows easy absorption, transport, and accumulation to target connective tissue. FORTIGEL® provides 5 g hypoallergenic protein per serving from a sustainable protein source. The lower dose of collagen peptides decreases excess oxalate production, compared to higher-dose collagen and gelatin products.
Hyaluronic Acid Extract
Mobilee® is a patented rooster comb extract rich in high molecular weight hyaluronic acid (HA), which is responsible for the viscoelastic, lubricating properties of synovial fluid. This extract also contains collagen and other glycosaminoglycans (GAGs). Hyaluronic acid also plays a role in the biophysical, biochemical and cell regulation processes in joint synovial tissues. Scientific evidence shows Mobilee® supports chrondrocytes and synovial cell function, and is two to four times more active than regular HA in supporting synovial fluid health. The latest clinical research includes HA in proactive and maintenance approaches to joint care and supports normal range-of-motion. Research suggests Mobilee® supports the quality of synovial fluid by positively influencing synovial HA concentration, and by reducing the expression of degradative factors in synovial fluid.
Type I Collagen and Mucopolysaccharides
Tendaxion® is a combination of type I collagen and mucopolysaccharides. Adult tendons, ligaments and fascial tissue are comprised mainly of type I collagen molecules organized into structural units. The molecular structure and organization of tendon, ligament and fascial collagen fibrils are key determinants in the ability of these tissues to endure mechanical force and fuel self-repair. While collagen provides much of tendon/ligament structure and strength, mucopolysaccharides are the “glue” that holds them together and allows them to stretch, flex, bend and maintain their resilience. Mucopolysaccharides are a critical component of extracellular matrix and are important in maintaining structural integrity, lubrication and spacing of collagen fibers. Furthermore, mucopolysaccharides have been shown to increase collagen and non-collagenous protein synthesis in cultures of bovine tenocytes and ligament cells. Tendaxion® has been shown to be efficacious in medial and lateral epicondyle tendon patients, Achilles tendon patients and plantar fascia.